Caño Negro is located in the northern region, 25 kilometers south of Los Chiles and 30 kilometers north of Upala.

From San José (Central Valley) to Caño Negro:

-Through Heredia on the road through Varablanca: Heredia (follow the signs to Poas Volcano or Varablanca), Barva, Cartagos, Varablanca, Chinchona, San Miguel, Río Cuarto, Venecia, Aguas Zarcas, Muelle de San Carlos, Pavón, Parque. From Parque, continue seven kilometers north to the “El Jobo” intersection. Go left on the highway (west) towards Caño Negro, about 25 kilometers.

-Through Alajuela on the road through Varablanca: Alaluela (follow signs to Poas Volcano or Varablanca), San Pedro de Poas, Poasito, Varablanca, Chinchona, San Miguel, Río Cuarto, Venecia, Aguas Zarcas, Muelle de San Carlos, Pavón, Parque, Caño Negro.

-Through Puerto Viejo de Sarapiquí: Selva Verde, Chilamate, Bajos de Chilamate, La Virgen, San Miguel, Río Cuarto, Venecia, Aguas Zarcas, Muelle de San Carlos, Pavón, Parque, Caño Negro.

-Through Sarchí, San Ramón or Naranjo: Follow signs to Ciudad Quesada, then to Muelle de San Carlos or Los Chiles. Alter arriving at Muelle de San Carlos (wide intersection with gas station) continue north, following the instructions given above.
From Arenal to Caño Negro:

-La Fortuna: Follow signs to Muelle de San Carlos or Los Chiles. At Muelle de San Carlos (wide intersection with gas station), turn left and go north toward Los Chiles, follow the instructions given above.
From Guanacaste:

-Southern Guanacaste (from the south of the peninsula to Tamarindo): Take the highway to the Río Tempisque bridge, continue north on the Pan-American Highway to Cañas and continue seven kilometers to Liberia (north). You will come to an intersection to Upala, which goes through Hacienda Tenorio, Río Naranjo, Bijagua, Canalete and Upala. From Upala, cross the metal bridge going to Colonia de Puntarenas, continue 9 kilometers and take the highway to the left to Caño Negro.

-Northern Guanacaste (from Tamarindo north): Go east to Liberia and then travel south until you get to the Upala intersection, then follow the directions given above.